Biomedical nanodevices, at the cutting edge of medical technology, leverage nanoscale materials and structures to revolutionize diagnostics, treatment, and monitoring in healthcare. These devices, such as nanosensors, nanorobots, and nanoparticle-based drug delivery systems, offer precise targeting, enhanced sensitivity, and reduced side effects compared to traditional methods. In diagnostics, nanodevices enable early disease detection through biomarker detection and imaging at the cellular and molecular levels. They also play a crucial role in personalized medicine by delivering therapeutic agents directly to diseased tissues while minimizing damage to healthy cells. Applications span various medical fields, including oncology, cardiology, neurology, and regenerative medicine. Challenges include ensuring biocompatibility, scalability of production, and navigating regulatory pathways for clinical approval. Ongoing research focuses on enhancing device functionality, improving biostability, and integrating nanotechnology with other medical technologies such as artificial intelligence and bioprinting.